Mihir Chavda to speak on zamamiphidin A at ACS Fall 2026
July 30, 2026
Mihir Chavda will give a talk at ACS Fall 2026, which runs from August 23 to 27 at McCormick Place in Chicago. He speaks on Thursday, August 27 at 11:20 AM in room W180, in the Division of Organic Chemistry’s session on Total Synthesis of Complex Molecules.
The talk is titled “Iodine(III)-mediated intramolecular oxamidation of unsaturated O-alkyl hydroxamates: Application to the tricyclic core and macrocyclic ring A of zamamiphidin A.”
It applies the group’s oxamidation chemistry — the iodine(III)-mediated cyclization of unsaturated O-alkyl hydroxamates, already used to reach the morphan core of madangamine D — to zamamiphidin A, one of the current targets in the total synthesis program. Like the other alkaloids in that group, it is built around the cage-like 2-azabicyclo[3.3.1]nonane ring system.
The talk is titled “Iodine(III)-mediated intramolecular oxamidation of unsaturated O-alkyl hydroxamates: Application to the tricyclic core and macrocyclic ring A of zamamiphidin A.”
It applies the group’s oxamidation chemistry — the iodine(III)-mediated cyclization of unsaturated O-alkyl hydroxamates, already used to reach the morphan core of madangamine D — to zamamiphidin A, one of the current targets in the total synthesis program. Like the other alkaloids in that group, it is built around the cage-like 2-azabicyclo[3.3.1]nonane ring system.